Genetic Polymorphisms and Forensic Efficiencies of a Set of Novel Autosomal InDel Markers in a Chinese Mongolian Group

Insertion/deletion (InDel) markers have been treated as a prospective and helpful aid in the fields of forensic human identifications and biogeography origin researches for the past few years. In this study, we analyzed genetic polymorphisms and forensic efficiencies of 35 InDels in a novel multiple...

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Autores principales: Zhang, Wenqing, Jin, Xiaoye, Wang, Yijie, Kong, Tingting, Cui, Wei, Chen, Chong, Guo, Yuxin, Zhu, Bofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970480/
https://www.ncbi.nlm.nih.gov/pubmed/31998787
http://dx.doi.org/10.1155/2020/3925189
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author Zhang, Wenqing
Jin, Xiaoye
Wang, Yijie
Kong, Tingting
Cui, Wei
Chen, Chong
Guo, Yuxin
Zhu, Bofeng
author_facet Zhang, Wenqing
Jin, Xiaoye
Wang, Yijie
Kong, Tingting
Cui, Wei
Chen, Chong
Guo, Yuxin
Zhu, Bofeng
author_sort Zhang, Wenqing
collection PubMed
description Insertion/deletion (InDel) markers have been treated as a prospective and helpful aid in the fields of forensic human identifications and biogeography origin researches for the past few years. In this study, we analyzed genetic polymorphisms and forensic efficiencies of 35 InDels in a novel multiplex PCR-InDel panel in a Chinese Mongolian group. All these 35 InDel loci were observed to conform to Hardy–Weinberg equilibrium and linkage equilibrium. The mean values of expected heterozygosity and observed heterozygosity were 0.4788 and 0.4852, respectively. Besides, the interpopulation differentiations and genetic distributions based on 35 InDels found that the Chinese Mongolian group might have closer genetic relationships and similar population genetic structures with East Asian populations.
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spelling pubmed-69704802020-01-29 Genetic Polymorphisms and Forensic Efficiencies of a Set of Novel Autosomal InDel Markers in a Chinese Mongolian Group Zhang, Wenqing Jin, Xiaoye Wang, Yijie Kong, Tingting Cui, Wei Chen, Chong Guo, Yuxin Zhu, Bofeng Biomed Res Int Research Article Insertion/deletion (InDel) markers have been treated as a prospective and helpful aid in the fields of forensic human identifications and biogeography origin researches for the past few years. In this study, we analyzed genetic polymorphisms and forensic efficiencies of 35 InDels in a novel multiplex PCR-InDel panel in a Chinese Mongolian group. All these 35 InDel loci were observed to conform to Hardy–Weinberg equilibrium and linkage equilibrium. The mean values of expected heterozygosity and observed heterozygosity were 0.4788 and 0.4852, respectively. Besides, the interpopulation differentiations and genetic distributions based on 35 InDels found that the Chinese Mongolian group might have closer genetic relationships and similar population genetic structures with East Asian populations. Hindawi 2020-01-07 /pmc/articles/PMC6970480/ /pubmed/31998787 http://dx.doi.org/10.1155/2020/3925189 Text en Copyright © 2020 Wenqing Zhang et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Wenqing
Jin, Xiaoye
Wang, Yijie
Kong, Tingting
Cui, Wei
Chen, Chong
Guo, Yuxin
Zhu, Bofeng
Genetic Polymorphisms and Forensic Efficiencies of a Set of Novel Autosomal InDel Markers in a Chinese Mongolian Group
title Genetic Polymorphisms and Forensic Efficiencies of a Set of Novel Autosomal InDel Markers in a Chinese Mongolian Group
title_full Genetic Polymorphisms and Forensic Efficiencies of a Set of Novel Autosomal InDel Markers in a Chinese Mongolian Group
title_fullStr Genetic Polymorphisms and Forensic Efficiencies of a Set of Novel Autosomal InDel Markers in a Chinese Mongolian Group
title_full_unstemmed Genetic Polymorphisms and Forensic Efficiencies of a Set of Novel Autosomal InDel Markers in a Chinese Mongolian Group
title_short Genetic Polymorphisms and Forensic Efficiencies of a Set of Novel Autosomal InDel Markers in a Chinese Mongolian Group
title_sort genetic polymorphisms and forensic efficiencies of a set of novel autosomal indel markers in a chinese mongolian group
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970480/
https://www.ncbi.nlm.nih.gov/pubmed/31998787
http://dx.doi.org/10.1155/2020/3925189
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