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Engineered IL-7 Receptor Enhances the Therapeutic Effect of AXL-CAR-T Cells on Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is a very aggressive malignant type of tumor that currently lacks effective targeted therapies. In hematological malignancies, chimeric antigen receptor T (CAR-T) cells have shown very significant antitumor ability; however, in solid tumors, the efficacy is poor....

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Detalles Bibliográficos
Autores principales: Zhao, Zhenhui, Li, Yan, Liu, Wei, Li, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970498/
https://www.ncbi.nlm.nih.gov/pubmed/31998790
http://dx.doi.org/10.1155/2020/4795171

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