Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity

Adipose tissue macrophages (ATMs) play a central role in tissue remodeling and homeostasis. However, whether ATMs promote adipose angiogenesis in obesity remains unclear. We examined the impact of ATMs deletion on adipose angiogenesis and tissue expansion in the epididymal white adipose tissue (eWAT...

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Detalles Bibliográficos
Autores principales: Onogi, Yasuhiro, Wada, Tsutomu, Okekawa, Akira, Matsuzawa, Takatoshi, Watanabe, Eri, Ikeda, Keisuke, Nakano, Minoru, Kitada, Munehiro, Koya, Daisuke, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970998/
https://www.ncbi.nlm.nih.gov/pubmed/31959796
http://dx.doi.org/10.1038/s41598-019-57368-w

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