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Cellular expression and function of naturally occurring variants of the human ABCG2 multidrug transporter
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics; thus the relatively frequent polymorphic and mutant ABCG2 variants in the population may significantly alter disease conditions and pharmacological effects. Low-level or non-functiona...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971004/ https://www.ncbi.nlm.nih.gov/pubmed/31254042 http://dx.doi.org/10.1007/s00018-019-03186-2 |