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Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
Ionising radiation (IR) is a recognised carcinogen responsible for cancer development in patients previously treated using radiotherapy, and in individuals exposed as a result of accidents at nuclear energy plants. However, the mutational signatures induced by distinct types and doses of radiation a...
Autores principales: | Rose Li, Yun, Halliwill, Kyle D., Adams, Cassandra J., Iyer, Vivek, Riva, Laura, Mamunur, Rashid, Jen, Kuang-Yu, del Rosario, Reyno, Fredlund, Erik, Hirst, Gillian, Alexandrov, Ludmil B., Adams, David, Balmain, Allan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971050/ https://www.ncbi.nlm.nih.gov/pubmed/31959748 http://dx.doi.org/10.1038/s41467-019-14261-4 |
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