Granzyme A in Chikungunya and Other Arboviral Infections

Granzyme A (GzmA) is secreted by cytotoxic lymphocytes and has traditionally been viewed as a mediator of cell death. However, a growing body of data suggests the physiological role of GzmA is promotion of inflammation. Here, we show that GzmA is significantly elevated in the sera of chikungunya vir...

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Detalles Bibliográficos
Autores principales: Schanoski, Alessandra S., Le, Thuy T., Kaiserman, Dion, Rowe, Caitlin, Prow, Natalie A., Barboza, Diego D., Santos, Cliomar A., Zanotto, Paolo M. A., Magalhães, Kelly G., Aurelio, Luigi, Muller, David, Young, Paul, Zhao, Peishen, Bird, Phillip I., Suhrbier, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971054/
https://www.ncbi.nlm.nih.gov/pubmed/31993061
http://dx.doi.org/10.3389/fimmu.2019.03083

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