Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers

Sarcomatoid clear-cell renal cell carcinomas (sRCC) are associated with dismal prognosis. Genomic alterations associated with sarcomatoid dedifferentiation are poorly characterized. We sought to define the genomic landscape of sRCC and uncover potentially actionable therapeutic targets. We assessed...

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Detalles Bibliográficos
Autores principales: Malouf, Gabriel G., Flippot, Ronan, Dong, Yiyu, Dinatale, Renzo G., Chen, Ying-Bei, Su, Xiaoping, Compérat, Eva, Rouprêt, Morgan, Mano, Roy, Blum, Kyle A., Yao, Hui, Mouawad, Roger, Spano, Jean-Philippe, Khayat, David, Karam, Jose A., Ho, Thai H., Tickoo, Satish K., Russo, Paul, Hsieh, James J., Tannir, Nizar M., Hakimi, Abraham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971072/
https://www.ncbi.nlm.nih.gov/pubmed/31959902
http://dx.doi.org/10.1038/s41598-020-57534-5

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