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Automated Detection of Autism Spectrum Disorder Using a Convolutional Neural Network

Background: Convolutional neural networks (CNN) have enabled significant progress in speech recognition, image classification, automotive software engineering, and neuroscience. This impressive progress is largely due to a combination of algorithmic breakthroughs, computation resource improvements,...

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Autores principales: Sherkatghanad, Zeinab, Akhondzadeh, Mohammadsadegh, Salari, Soorena, Zomorodi-Moghadam, Mariam, Abdar, Moloud, Acharya, U. Rajendra, Khosrowabadi, Reza, Salari, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971220/
https://www.ncbi.nlm.nih.gov/pubmed/32009868
http://dx.doi.org/10.3389/fnins.2019.01325
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author Sherkatghanad, Zeinab
Akhondzadeh, Mohammadsadegh
Salari, Soorena
Zomorodi-Moghadam, Mariam
Abdar, Moloud
Acharya, U. Rajendra
Khosrowabadi, Reza
Salari, Vahid
author_facet Sherkatghanad, Zeinab
Akhondzadeh, Mohammadsadegh
Salari, Soorena
Zomorodi-Moghadam, Mariam
Abdar, Moloud
Acharya, U. Rajendra
Khosrowabadi, Reza
Salari, Vahid
author_sort Sherkatghanad, Zeinab
collection PubMed
description Background: Convolutional neural networks (CNN) have enabled significant progress in speech recognition, image classification, automotive software engineering, and neuroscience. This impressive progress is largely due to a combination of algorithmic breakthroughs, computation resource improvements, and access to a large amount of data. Method: In this paper, we focus on the automated detection of autism spectrum disorder (ASD) using CNN with a brain imaging dataset. We detected ASD patients using most common resting-state functional magnetic resonance imaging (fMRI) data from a multi-site dataset named the Autism Brain Imaging Exchange (ABIDE). The proposed approach was able to classify ASD and control subjects based on the patterns of functional connectivity. Results: Our experimental outcomes indicate that the proposed model is able to detect ASD correctly with an accuracy of 70.22% using the ABIDE I dataset and the CC400 functional parcellation atlas of the brain. Also, the CNN model developed used fewer parameters than the state-of-art techniques and is hence computationally less intensive. Our developed model is ready to be tested with more data and can be used to prescreen ASD patients.
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spelling pubmed-69712202020-02-01 Automated Detection of Autism Spectrum Disorder Using a Convolutional Neural Network Sherkatghanad, Zeinab Akhondzadeh, Mohammadsadegh Salari, Soorena Zomorodi-Moghadam, Mariam Abdar, Moloud Acharya, U. Rajendra Khosrowabadi, Reza Salari, Vahid Front Neurosci Neuroscience Background: Convolutional neural networks (CNN) have enabled significant progress in speech recognition, image classification, automotive software engineering, and neuroscience. This impressive progress is largely due to a combination of algorithmic breakthroughs, computation resource improvements, and access to a large amount of data. Method: In this paper, we focus on the automated detection of autism spectrum disorder (ASD) using CNN with a brain imaging dataset. We detected ASD patients using most common resting-state functional magnetic resonance imaging (fMRI) data from a multi-site dataset named the Autism Brain Imaging Exchange (ABIDE). The proposed approach was able to classify ASD and control subjects based on the patterns of functional connectivity. Results: Our experimental outcomes indicate that the proposed model is able to detect ASD correctly with an accuracy of 70.22% using the ABIDE I dataset and the CC400 functional parcellation atlas of the brain. Also, the CNN model developed used fewer parameters than the state-of-art techniques and is hence computationally less intensive. Our developed model is ready to be tested with more data and can be used to prescreen ASD patients. Frontiers Media S.A. 2020-01-14 /pmc/articles/PMC6971220/ /pubmed/32009868 http://dx.doi.org/10.3389/fnins.2019.01325 Text en Copyright © 2020 Sherkatghanad, Akhondzadeh, Salari, Zomorodi-Moghadam, Abdar, Acharya, Khosrowabadi and Salari. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Sherkatghanad, Zeinab
Akhondzadeh, Mohammadsadegh
Salari, Soorena
Zomorodi-Moghadam, Mariam
Abdar, Moloud
Acharya, U. Rajendra
Khosrowabadi, Reza
Salari, Vahid
Automated Detection of Autism Spectrum Disorder Using a Convolutional Neural Network
title Automated Detection of Autism Spectrum Disorder Using a Convolutional Neural Network
title_full Automated Detection of Autism Spectrum Disorder Using a Convolutional Neural Network
title_fullStr Automated Detection of Autism Spectrum Disorder Using a Convolutional Neural Network
title_full_unstemmed Automated Detection of Autism Spectrum Disorder Using a Convolutional Neural Network
title_short Automated Detection of Autism Spectrum Disorder Using a Convolutional Neural Network
title_sort automated detection of autism spectrum disorder using a convolutional neural network
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971220/
https://www.ncbi.nlm.nih.gov/pubmed/32009868
http://dx.doi.org/10.3389/fnins.2019.01325
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