P53 and Parkin co-regulate mitophagy in bone marrow mesenchymal stem cells to promote the repair of early steroid-induced osteonecrosis of the femoral head

Survival and stemness of bone marrow mesenchymal stem cells (BMSCs) in osteonecrotic areas are especially important in the treatment of early steroid-induced osteonecrosis of the femoral head (ONFH). We had previously used BMSCs to repair early steroid-induced ONFH, but the transplanted BMSCs underw...

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Detalles Bibliográficos
Autores principales: Zhang, Fei, Peng, Wuxun, Zhang, Jian, Dong, Wentao, Wu, Jianhua, Wang, Tao, Xie, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971291/
https://www.ncbi.nlm.nih.gov/pubmed/31959744
http://dx.doi.org/10.1038/s41419-020-2238-1

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