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Persistent wheezing caused by carvedilol overdose in a non‐asthmatic man

BACKGROUND: Cardiovascular dysfunction is the main manifestation of β‐blocker intoxication; however, respiratory manifestations have rarely been reported. CASE PRESENTATION: A 41‐year‐old man, who had ingested 300 mg carvedilol in a suicide attempt, was transferred to our emergency department. The p...

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Autores principales: Nakanishi, Misuzu, Kuriyama, Akira, Onodera, Mutsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971462/
https://www.ncbi.nlm.nih.gov/pubmed/31988787
http://dx.doi.org/10.1002/ams2.475
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author Nakanishi, Misuzu
Kuriyama, Akira
Onodera, Mutsuo
author_facet Nakanishi, Misuzu
Kuriyama, Akira
Onodera, Mutsuo
author_sort Nakanishi, Misuzu
collection PubMed
description BACKGROUND: Cardiovascular dysfunction is the main manifestation of β‐blocker intoxication; however, respiratory manifestations have rarely been reported. CASE PRESENTATION: A 41‐year‐old man, who had ingested 300 mg carvedilol in a suicide attempt, was transferred to our emergency department. The patient had wheezing on arrival; however, he had no known history of bronchial asthma. In the absence of signs of heart failure, we gave the patient inhaled procaterol, a short‐acting β2 agonist. The wheezing disappeared approximately 60 h after carvedilol ingestion and did not recur thereafter. CONCLUSION: We report a case of wheezing caused by carvedilol intoxication. Although rare, clinicians should recognize that wheezing or bronchospasm can develop following β‐blocker intoxication, for which a short‐acting β2 agonist could be indicated.
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spelling pubmed-69714622020-01-27 Persistent wheezing caused by carvedilol overdose in a non‐asthmatic man Nakanishi, Misuzu Kuriyama, Akira Onodera, Mutsuo Acute Med Surg Case Reports BACKGROUND: Cardiovascular dysfunction is the main manifestation of β‐blocker intoxication; however, respiratory manifestations have rarely been reported. CASE PRESENTATION: A 41‐year‐old man, who had ingested 300 mg carvedilol in a suicide attempt, was transferred to our emergency department. The patient had wheezing on arrival; however, he had no known history of bronchial asthma. In the absence of signs of heart failure, we gave the patient inhaled procaterol, a short‐acting β2 agonist. The wheezing disappeared approximately 60 h after carvedilol ingestion and did not recur thereafter. CONCLUSION: We report a case of wheezing caused by carvedilol intoxication. Although rare, clinicians should recognize that wheezing or bronchospasm can develop following β‐blocker intoxication, for which a short‐acting β2 agonist could be indicated. John Wiley and Sons Inc. 2019-12-14 /pmc/articles/PMC6971462/ /pubmed/31988787 http://dx.doi.org/10.1002/ams2.475 Text en © 2019 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Nakanishi, Misuzu
Kuriyama, Akira
Onodera, Mutsuo
Persistent wheezing caused by carvedilol overdose in a non‐asthmatic man
title Persistent wheezing caused by carvedilol overdose in a non‐asthmatic man
title_full Persistent wheezing caused by carvedilol overdose in a non‐asthmatic man
title_fullStr Persistent wheezing caused by carvedilol overdose in a non‐asthmatic man
title_full_unstemmed Persistent wheezing caused by carvedilol overdose in a non‐asthmatic man
title_short Persistent wheezing caused by carvedilol overdose in a non‐asthmatic man
title_sort persistent wheezing caused by carvedilol overdose in a non‐asthmatic man
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971462/
https://www.ncbi.nlm.nih.gov/pubmed/31988787
http://dx.doi.org/10.1002/ams2.475
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