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Towards mapping the 3D genome through high speed single-molecule tracking of functional transcription factors in single living cells
How genomic DNA is organized in the nucleus is a long-standing question. We describe a single-molecule bioimaging method utilizing super-localization precision coupled to fully quantitative image analysis tools, towards determining snapshots of parts of the 3D genome architecture of model eukaryote...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971689/ https://www.ncbi.nlm.nih.gov/pubmed/31252059 http://dx.doi.org/10.1016/j.ymeth.2019.06.021 |