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Cofilin, a Master Node Regulating Cytoskeletal Pathogenesis in Alzheimer’s Disease
The defining pathological hallmarks of Alzheimer’s disease (AD) are proteinopathies marked by the amyloid-β (Aβ) peptide and hyperphosphorylated tau. In addition, Hirano bodies and cofilin-actin rods are extensively found in AD brains, both of which are associated with the actin cytoskeleton. The a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971827/ https://www.ncbi.nlm.nih.gov/pubmed/31594228 http://dx.doi.org/10.3233/JAD-190585 |