Life-extending dietary restriction, but not dietary supplementation of branched-chain amino acids, can increase organismal oxidation rates of individual branched-chain amino acids by grasshoppers

BACKGROUND: Life-extending dietary restriction increases energy demands. Branched-chain amino acids (BCAAs), at high levels, may be detrimental to healthspan by activating the mechanistic Target of Rapamycin (mTOR). Whether organismal oxidation of BCAAs increases upon dietary restriction is unknown....

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Detalles Bibliográficos
Autores principales: Hatle, J.D., Karjasevic, A., Rehfeldt, E., Nagle, F.S., Milano, L.J., Patel, S., Hiatt, D., McCue, M.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971830/
https://www.ncbi.nlm.nih.gov/pubmed/31984246
http://dx.doi.org/10.3233/NHA-190073

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