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Hypoxia induced LUCAT1/PTBP1 axis modulates cancer cell viability and chemotherapy response
BACKGROUND: Hypoxic tumors are refractory to DNA damage drugs. However, the underlying mechanism has yet to be elucidated. We aimed to identify lncRNAs that upregulated under hypoxia and their effects on colorectal cancer (CRC). METHODS: CRC cells were treated with 1% O(2) to identify lncRNAs that u...
Autores principales: | Huan, Lin, Guo, Tianan, Wu, Yangjun, Xu, Linguo, Huang, Shenglin, Xu, Ye, Liang, Linhui, He, Xianghuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971890/ https://www.ncbi.nlm.nih.gov/pubmed/31964396 http://dx.doi.org/10.1186/s12943-019-1122-z |
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