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Non-invasive MRI quantification of cerebrospinal fluid dynamics in amyotrophic lateral sclerosis patients
BACKGROUND: Developing novel therapeutic agents to treat amyotrophic lateral sclerosis (ALS) has been difficult due to multifactorial pathophysiologic processes at work. Intrathecal drug administration shows promise due to close proximity of cerebrospinal fluid (CSF) to affected tissues. Development...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971921/ https://www.ncbi.nlm.nih.gov/pubmed/31959193 http://dx.doi.org/10.1186/s12987-019-0164-3 |