Non-invasive MRI quantification of cerebrospinal fluid dynamics in amyotrophic lateral sclerosis patients

BACKGROUND: Developing novel therapeutic agents to treat amyotrophic lateral sclerosis (ALS) has been difficult due to multifactorial pathophysiologic processes at work. Intrathecal drug administration shows promise due to close proximity of cerebrospinal fluid (CSF) to affected tissues. Development...

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Detalles Bibliográficos
Autores principales: Sass, Lucas R., Khani, Mohammadreza, Romm, Jacob, Schmid Daners, Marianne, McCain, Kyle, Freeman, Tavara, Carter, Gregory T., Weeks, Douglas L., Petersen, Brian, Aldred, Jason, Wingett, Dena, Martin, Bryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971921/
https://www.ncbi.nlm.nih.gov/pubmed/31959193
http://dx.doi.org/10.1186/s12987-019-0164-3

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