A first Japanese case of neuroendocrine prostate cancer accompanied by lung and brain metastasis with somatic and germline BRCA2 mutation

Germline mutations and copy number changes in DNA damage repair (DDR) genes such as BRCA2 are associated with aggressive forms of prostate cancer (PCa). Although the prevalence of BRCA2 variants in PCa is increasing in Japan, the genomic and biological implications in Japanese patients are unclear....

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Detalles Bibliográficos
Autores principales: Kosaka, Takeo, Hongo, Hiroshi, Aimono, Eriko, Matsumoto, Kazuhiro, Hayashida, Tetsu, Mikami, Shuji, Nishihara, Hiroshi, Oya, Mototsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972566/
https://www.ncbi.nlm.nih.gov/pubmed/31631483
http://dx.doi.org/10.1111/pin.12860

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