IL‐32 and its splice variants are associated with protection against Mycobacterium tuberculosis infection and skewing of Th1/Th17 cytokines

Studies in IL‐32 transgenic mice and in vitro suggest that IL‐32 may have protective effects against Mycobacterium tuberculosis, but so far there are barely any studies in humans. We studied the role of IL‐32 and its splice variants in tuberculosis (TB) in vivo and in vitro. Blood transcriptional an...

Descripción completa

Detalles Bibliográficos
Autores principales: Koeken, Valerie A. C. M., Verrall, Ayesha J., Ardiansyah, Edwin, Apriani, Lika, dos Santos, Jéssica C., Kumar, Vinod, Alisjahbana, Bachti, Hill, Philip C., Joosten, Leo A. B., van Crevel, Reinout, van Laarhoven, Arjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Host Defense & Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972663/
https://www.ncbi.nlm.nih.gov/pubmed/31378983
http://dx.doi.org/10.1002/JLB.4AB0219-071R

Ejemplares similares

Ejemplares similares