Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing

Natural products (NPs) from microorganisms have been important sources for discovering new therapeutic and chemical entities. While their corresponding biosynthetic gene clusters (BGCs) can be easily identified by gene‐sequence‐similarity‐based bioinformatics strategies, the actual access to these N...

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Detalles Bibliográficos
Autores principales: Bode, Edna, Heinrich, Antje K., Hirschmann, Merle, Abebew, Desalegne, Shi, Yan‐Ni, Vo, Tien Duy, Wesche, Frank, Shi, Yi‐Ming, Grün, Peter, Simonyi, Svenja, Keller, Nadine, Engel, Yvonne, Wenski, Sebastian, Bennet, Reuel, Beyer, Sophie, Bischoff, Iris, Buaya, Anthony, Brandt, Sophie, Cakmak, Ibrahim, Çimen, Harun, Eckstein, Simone, Frank, Denia, Fürst, Robert, Gand, Martin, Geisslinger, Gerd, Hazir, Selcuk, Henke, Marina, Heermann, Ralf, Lecaudey, Virginie, Schäfer, Wilhelm, Schiffmann, Susanne, Schüffler, Anja, Schwenk, Rebecca, Skaljac, Marisa, Thines, Eckhard, Thines, Marco, Ulshöfer, Thomas, Vilcinskas, Andreas, Wichelhaus, Thomas A., Bode, Helge B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972681/
https://www.ncbi.nlm.nih.gov/pubmed/31693786
http://dx.doi.org/10.1002/anie.201910563

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