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Silver‐Mediated Homochiral and Heterochiral α‐dC/β‐dC Base Pairs: Synthesis of α‐dC through Glycosylation and Impact of Consecutive, Isolated, and Multiple Metal Ion Pairs on DNA Stability
Isolated and consecutive heterochiral α‐dC– base pairs have been incorporated into 12‐mer oligonucleotide duplexes at various positions, thereby replacing Watson–Crick pairs. To this end, a new synthesis of the α‐d anomer of dC has been developed, and oligonucleotides containing α‐dC residues have b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972701/ https://www.ncbi.nlm.nih.gov/pubmed/31583755 http://dx.doi.org/10.1002/chem.201903915 |