Stenosis coexists with compromised α1-adrenergic contractions in the ascending aorta of a mouse model of Williams-Beuren syndrome

Williams-Beuren syndrome (WBS) is a rare disorder caused by a heterozygous deletion of 26–28 contiguous genes that affects the brain and cardiovascular system. Here, we investigated whether WBS affects aortic structure and function in the complete deletion (CD) mouse model harbouring the most common...

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Detalles Bibliográficos
Autores principales: Jiménez-Altayó, Francesc, Ortiz-Romero, Paula, Puertas-Umbert, Lídia, Dantas, Ana Paula, Pérez, Belén, Vila, Elisabet, D’Ocon, Pilar, Campuzano, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972706/
https://www.ncbi.nlm.nih.gov/pubmed/31965005
http://dx.doi.org/10.1038/s41598-020-57803-3

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