HBV X protein mutations affect HBV transcription and association of histone-modifying enzymes with covalently closed circular DNA

The hepatitis B X protein (HBx) plays a role in the epigenetic regulation of hepatitis B virus (HBV) replication. This study investigated the effects of HBx mutations on HBV transcription and the recruitment of HBx, histone acetyl-transferase P300 and histone deacetylase 1 (HDAC1) to circularized HB...

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Detalles Bibliográficos
Autores principales: Chong, Chun Kong, Cheng, Ching Yan Serene, Tsoi, Sin Yi Jasmine, Huang, Fung-Yu, Liu, Fen, Fung, James, Seto, Wai-Kay, Lai, Keane K.-Y., Lai, Ching-Lung, Yuen, Man-Fung, Wong, Danny Ka-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972884/
https://www.ncbi.nlm.nih.gov/pubmed/31964944
http://dx.doi.org/10.1038/s41598-020-57637-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972884/
https://www.ncbi.nlm.nih.gov/pubmed/31964944
http://dx.doi.org/10.1038/s41598-020-57637-z

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