Non-invasive characterization of human bone marrow stimulation and reconstitution by cell-free messenger RNA sequencing

Circulating cell-free mRNA (cf-mRNA) holds great promise as a non-invasive diagnostic biomarker. However, cf-mRNA composition and its potential clinical applications remain largely unexplored. Here we show, using Next Generation Sequencing-based profiling, that cf-mRNA is enriched in transcripts der...

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Detalles Bibliográficos
Autores principales: Ibarra, Arkaitz, Zhuang, Jiali, Zhao, Yue, Salathia, Neeraj S., Huang, Vera, Acosta, Alexander D., Aballi, Jonathan, Toden, Shusuke, Karns, Amy P., Purnajo, Intan, Parks, Julianna R., Guo, Lucy, Mason, James, Sigal, Darren, Nova, Tina S., Quake, Stephen R., Nerenberg, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972916/
https://www.ncbi.nlm.nih.gov/pubmed/31964864
http://dx.doi.org/10.1038/s41467-019-14253-4

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