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Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS)
The yeast fatty acid synthase (FAS) is a barrel-shaped 2.6 MDa complex. Upon barrel-formation, two multidomain subunits, each more than 200 kDa large, intertwine to form a heterododecameric complex that buries 170,000 Å(2) of protein surface. In spite of the rich knowledge about yeast FAS in structu...
Autores principales: | Fischer, Manuel, Joppe, Mirko, Mulinacci, Barbara, Vollrath, Ronnald, Konstantinidis, Kosta, Kötter, Peter, Ciccarelli, Luciano, Vonck, Janet, Oesterhelt, Dieter, Grininger, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972935/ https://www.ncbi.nlm.nih.gov/pubmed/31964902 http://dx.doi.org/10.1038/s41598-020-57418-8 |
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