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Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus

Human status epilepticus (SE) is associated with a pathological reduction in cerebral blood flow termed the inverse hemodynamic response (IHR). Canonical transient receptor potential 3 (TRPC3) channels are integral to the propagation of seizures in SE, and vascular smooth muscle cell (VSMC) TRPC3 ch...

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Detalles Bibliográficos
Autores principales: Cozart, Michael A., Phelan, Kevin D., Wu, Hong, Mu, Shengyu, Birnbaumer, Lutz, Rusch, Nancy J., Zheng, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972937/
https://www.ncbi.nlm.nih.gov/pubmed/31964991
http://dx.doi.org/10.1038/s41598-020-57733-0