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Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus
Human status epilepticus (SE) is associated with a pathological reduction in cerebral blood flow termed the inverse hemodynamic response (IHR). Canonical transient receptor potential 3 (TRPC3) channels are integral to the propagation of seizures in SE, and vascular smooth muscle cell (VSMC) TRPC3 ch...
Autores principales: | Cozart, Michael A., Phelan, Kevin D., Wu, Hong, Mu, Shengyu, Birnbaumer, Lutz, Rusch, Nancy J., Zheng, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972937/ https://www.ncbi.nlm.nih.gov/pubmed/31964991 http://dx.doi.org/10.1038/s41598-020-57733-0 |
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