Extensive Structure–Activity Relationship Study of Albicidin's C‐Terminal Dipeptidic p‐Aminobenzoic Acid Moiety

Albicidin is a recently described natural product that strongly inhibits bacterial DNA gyrase. The pronounced activity, particularly against Gram‐negative bacteria, turns it into a promising lead structure for an antibacterial drug. Hence, structure–activity relationship studies are key for the in‐d...

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Detalles Bibliográficos
Autores principales: Behroz, Iraj, Durkin, Patrick, Grätz, Stefan, Seidel, Maria, Rostock, Lida, Spinczyk, Marcello, Weston, John B., Süssmuth, Roderich D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972991/
https://www.ncbi.nlm.nih.gov/pubmed/31642561
http://dx.doi.org/10.1002/chem.201904752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972991/
https://www.ncbi.nlm.nih.gov/pubmed/31642561
http://dx.doi.org/10.1002/chem.201904752

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