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Extensive Structure–Activity Relationship Study of Albicidin's C‐Terminal Dipeptidic p‐Aminobenzoic Acid Moiety
Albicidin is a recently described natural product that strongly inhibits bacterial DNA gyrase. The pronounced activity, particularly against Gram‐negative bacteria, turns it into a promising lead structure for an antibacterial drug. Hence, structure–activity relationship studies are key for the in‐d...
Autores principales: | Behroz, Iraj, Durkin, Patrick, Grätz, Stefan, Seidel, Maria, Rostock, Lida, Spinczyk, Marcello, Weston, John B., Süssmuth, Roderich D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972991/ https://www.ncbi.nlm.nih.gov/pubmed/31642561 http://dx.doi.org/10.1002/chem.201904752 |
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