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Site‐Specific Encoding of Photoactivity in Antibodies Enables Light‐Mediated Antibody–Antigen Binding on Live Cells

Antibodies have found applications in several fields, including, medicine, diagnostics, and nanotechnology, yet methods to modulate antibody–antigen binding using an external agent remain limited. Here, we have developed photoactive antibody fragments by genetic site‐specific replacement of single t...

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Detalles Bibliográficos
Autores principales: Bridge, Thomas, Shaikh, Saher A., Thomas, Paul, Botta, Joaquin, McCormick, Peter J., Sachdeva, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973043/
https://www.ncbi.nlm.nih.gov/pubmed/31609054
http://dx.doi.org/10.1002/anie.201908655

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