Improving comparability between qPCR‐based telomere studies

Comparability of findings from qPCR‐based telomere studies is hampered by such measurement results being assay‐specific, precluding a direct quantitative comparisons of observed differences and/or slopes of associations between studies. It is proposed that this can be partially alleviated by express...

Descripción completa

Detalles Bibliográficos
Autor principal: Verhulst, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
News and Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973063/
https://www.ncbi.nlm.nih.gov/pubmed/31680455
http://dx.doi.org/10.1111/1755-0998.13114
_version_ 1783489967198044160
author Verhulst, Simon
author_facet Verhulst, Simon
author_sort Verhulst, Simon
collection PubMed
description Comparability of findings from qPCR‐based telomere studies is hampered by such measurement results being assay‐specific, precluding a direct quantitative comparisons of observed differences and/or slopes of associations between studies. It is proposed that this can be partially alleviated by expressing qPCR‐based telomere data as Z‐scores.
format Online
Article
Text
id pubmed-6973063
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-69730632020-01-27 Improving comparability between qPCR‐based telomere studies Verhulst, Simon Mol Ecol Resour News and Views Comparability of findings from qPCR‐based telomere studies is hampered by such measurement results being assay‐specific, precluding a direct quantitative comparisons of observed differences and/or slopes of associations between studies. It is proposed that this can be partially alleviated by expressing qPCR‐based telomere data as Z‐scores. John Wiley and Sons Inc. 2019-11-22 2020-01 /pmc/articles/PMC6973063/ /pubmed/31680455 http://dx.doi.org/10.1111/1755-0998.13114 Text en © 2019 The Authors. Molecular Ecology Resources published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle News and Views
Verhulst, Simon
Improving comparability between qPCR‐based telomere studies
title Improving comparability between qPCR‐based telomere studies
title_full Improving comparability between qPCR‐based telomere studies
title_fullStr Improving comparability between qPCR‐based telomere studies
title_full_unstemmed Improving comparability between qPCR‐based telomere studies
title_short Improving comparability between qPCR‐based telomere studies
title_sort improving comparability between qpcr‐based telomere studies
topic News and Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973063/
https://www.ncbi.nlm.nih.gov/pubmed/31680455
http://dx.doi.org/10.1111/1755-0998.13114
work_keys_str_mv AT verhulstsimon improvingcomparabilitybetweenqpcrbasedtelomerestudies

Ejemplares similares