Assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home

Vitamin K antagonists are widely used, yet have a slim therapeutic margin and high iatrogenicity. Patients are monitored through international normalised ratio (INR) by venipuncture, but coagulometers could measure INR by capillary puncture. This prospective study evaluated the clinical concordance...

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Autores principales: Sikirdji, Chloé, Costa, David, Alonso, Sandrine, Clape, Jean‐François, Amouyal, Michel, de Waziere, Benoît, Fabbro‐Peray, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973070/
https://www.ncbi.nlm.nih.gov/pubmed/31713344
http://dx.doi.org/10.1111/imj.14626
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author Sikirdji, Chloé
Costa, David
Alonso, Sandrine
Clape, Jean‐François
Amouyal, Michel
de Waziere, Benoît
Fabbro‐Peray, Pascale
author_facet Sikirdji, Chloé
Costa, David
Alonso, Sandrine
Clape, Jean‐François
Amouyal, Michel
de Waziere, Benoît
Fabbro‐Peray, Pascale
author_sort Sikirdji, Chloé
collection PubMed
description Vitamin K antagonists are widely used, yet have a slim therapeutic margin and high iatrogenicity. Patients are monitored through international normalised ratio (INR) by venipuncture, but coagulometers could measure INR by capillary puncture. This prospective study evaluated the clinical concordance of capillary INR versus venous INR in 31 nursing home patients. Concordance was good and mean time in therapeutic range (TTR) markedly increased. Capillary INR is thus reliable, could improve TTR and decrease iatrogenicity.
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spelling pubmed-69730702020-01-27 Assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home Sikirdji, Chloé Costa, David Alonso, Sandrine Clape, Jean‐François Amouyal, Michel de Waziere, Benoît Fabbro‐Peray, Pascale Intern Med J Brief Communications Vitamin K antagonists are widely used, yet have a slim therapeutic margin and high iatrogenicity. Patients are monitored through international normalised ratio (INR) by venipuncture, but coagulometers could measure INR by capillary puncture. This prospective study evaluated the clinical concordance of capillary INR versus venous INR in 31 nursing home patients. Concordance was good and mean time in therapeutic range (TTR) markedly increased. Capillary INR is thus reliable, could improve TTR and decrease iatrogenicity. John Wiley & Sons Australia, Ltd 2019-11-11 2019-11 /pmc/articles/PMC6973070/ /pubmed/31713344 http://dx.doi.org/10.1111/imj.14626 Text en © 2019 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Brief Communications
Sikirdji, Chloé
Costa, David
Alonso, Sandrine
Clape, Jean‐François
Amouyal, Michel
de Waziere, Benoît
Fabbro‐Peray, Pascale
Assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home
title Assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home
title_full Assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home
title_fullStr Assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home
title_full_unstemmed Assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home
title_short Assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home
title_sort assessment of agreement and time in therapeutic range of capillary versus venous international normalised ratio in frail elderly people in a nursing home
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973070/
https://www.ncbi.nlm.nih.gov/pubmed/31713344
http://dx.doi.org/10.1111/imj.14626
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