Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database

WHAT IS KNOWN AND OBJECTIVE: We report a special case of fenofibrate‐induced acute severe DILI with sudden onset and rapid recovery, which is different from those in the LiverTox database. CASE SUMMARY DESCRIPTION: The acute severe DILI occurred within only 4 days after fenofibrate initial treatment...

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Detalles Bibliográficos
Autores principales: Ma, Shizhan, Liu, Shudong, Wang, Qi, Chen, Lijuan, Yang, Ping, Sun, Huihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973072/
https://www.ncbi.nlm.nih.gov/pubmed/31518450
http://dx.doi.org/10.1111/jcpt.13042
Descripción
Sumario:WHAT IS KNOWN AND OBJECTIVE: We report a special case of fenofibrate‐induced acute severe DILI with sudden onset and rapid recovery, which is different from those in the LiverTox database. CASE SUMMARY DESCRIPTION: The acute severe DILI occurred within only 4 days after fenofibrate initial treatment for hypertriglyceridemia. Liver enzyme levels eventually declined to normal within two weeks after the discontinuation of fenofibrate. WHAT IS NEW AND CONCLUSION: Early detection of elevated hepatic enzymes after fenofibrate initial treatment helps physicians to avoid delayed diagnosis and subsequent treatment.

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