Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database

WHAT IS KNOWN AND OBJECTIVE: We report a special case of fenofibrate‐induced acute severe DILI with sudden onset and rapid recovery, which is different from those in the LiverTox database. CASE SUMMARY DESCRIPTION: The acute severe DILI occurred within only 4 days after fenofibrate initial treatment...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Shizhan, Liu, Shudong, Wang, Qi, Chen, Lijuan, Yang, Ping, Sun, Huihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973072/
https://www.ncbi.nlm.nih.gov/pubmed/31518450
http://dx.doi.org/10.1111/jcpt.13042
_version_ 1783489969404248064
author Ma, Shizhan
Liu, Shudong
Wang, Qi
Chen, Lijuan
Yang, Ping
Sun, Huihuan
author_facet Ma, Shizhan
Liu, Shudong
Wang, Qi
Chen, Lijuan
Yang, Ping
Sun, Huihuan
author_sort Ma, Shizhan
collection PubMed
description WHAT IS KNOWN AND OBJECTIVE: We report a special case of fenofibrate‐induced acute severe DILI with sudden onset and rapid recovery, which is different from those in the LiverTox database. CASE SUMMARY DESCRIPTION: The acute severe DILI occurred within only 4 days after fenofibrate initial treatment for hypertriglyceridemia. Liver enzyme levels eventually declined to normal within two weeks after the discontinuation of fenofibrate. WHAT IS NEW AND CONCLUSION: Early detection of elevated hepatic enzymes after fenofibrate initial treatment helps physicians to avoid delayed diagnosis and subsequent treatment.
format Online
Article
Text
id pubmed-6973072
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-69730722020-01-27 Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database Ma, Shizhan Liu, Shudong Wang, Qi Chen, Lijuan Yang, Ping Sun, Huihuan J Clin Pharm Ther Case Reports WHAT IS KNOWN AND OBJECTIVE: We report a special case of fenofibrate‐induced acute severe DILI with sudden onset and rapid recovery, which is different from those in the LiverTox database. CASE SUMMARY DESCRIPTION: The acute severe DILI occurred within only 4 days after fenofibrate initial treatment for hypertriglyceridemia. Liver enzyme levels eventually declined to normal within two weeks after the discontinuation of fenofibrate. WHAT IS NEW AND CONCLUSION: Early detection of elevated hepatic enzymes after fenofibrate initial treatment helps physicians to avoid delayed diagnosis and subsequent treatment. John Wiley and Sons Inc. 2019-09-13 2020-02 /pmc/articles/PMC6973072/ /pubmed/31518450 http://dx.doi.org/10.1111/jcpt.13042 Text en © 2019 The Authors. Journal of Clinical Pharmacy and Therapeutics published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Ma, Shizhan
Liu, Shudong
Wang, Qi
Chen, Lijuan
Yang, Ping
Sun, Huihuan
Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database
title Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database
title_full Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database
title_fullStr Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database
title_full_unstemmed Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database
title_short Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database
title_sort fenofibrate‐induced hepatotoxicity: a case with a special feature that is different from those in the livertox database
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973072/
https://www.ncbi.nlm.nih.gov/pubmed/31518450
http://dx.doi.org/10.1111/jcpt.13042
work_keys_str_mv AT mashizhan fenofibrateinducedhepatotoxicityacasewithaspecialfeaturethatisdifferentfromthoseinthelivertoxdatabase
AT liushudong fenofibrateinducedhepatotoxicityacasewithaspecialfeaturethatisdifferentfromthoseinthelivertoxdatabase
AT wangqi fenofibrateinducedhepatotoxicityacasewithaspecialfeaturethatisdifferentfromthoseinthelivertoxdatabase
AT chenlijuan fenofibrateinducedhepatotoxicityacasewithaspecialfeaturethatisdifferentfromthoseinthelivertoxdatabase
AT yangping fenofibrateinducedhepatotoxicityacasewithaspecialfeaturethatisdifferentfromthoseinthelivertoxdatabase
AT sunhuihuan fenofibrateinducedhepatotoxicityacasewithaspecialfeaturethatisdifferentfromthoseinthelivertoxdatabase

Ejemplares similares