Impact of farnesoid X receptor single nucleotide polymorphisms on hepatic decompensation and mortality in cirrhotic patients with portal hypertension

BACKGROUND AND AIM: The nuclear farnesoid X receptor (FXR) regulates critical pathways of hepatic metabolism, inflammation, and gut mucosal barrier. Thus, we investigated the association of FXR‐single nucleotide polymorphism (SNPs) with hepatic decompensation and liver‐related mortality in patients...

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Detalles Bibliográficos
Autores principales: Semmler, Georg, Simbrunner, Benedikt, Scheiner, Bernhard, Schwabl, Philipp, Paternostro, Rafael, Bucsics, Theresa, Stättermayer, Albert Friedrich, Bauer, David, Pinter, Matthias, Ferenci, Peter, Trauner, Michael, Mandorfer, Mattias, Reiberger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Clinical Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973125/
https://www.ncbi.nlm.nih.gov/pubmed/31062417
http://dx.doi.org/10.1111/jgh.14700

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