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The role of integrins in the pathogenesis of inflammatory bowel disease: Approved and investigational anti‐integrin therapies

Inflammatory bowel disease (IBD) is characterized by uncontrolled inflammation in the gastrointestinal tract. The underlying pathobiology of IBD includes an increase in infiltrating gut‐homing lymphocytes. Although lymphocyte homing is typically a tightly regulated and stepwise process involving mul...

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Detalles Bibliográficos
Autores principales: Dotan, Iris, Allez, Matthieu, Danese, Silvio, Keir, Mary, Tole, Swati, McBride, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973243/
https://www.ncbi.nlm.nih.gov/pubmed/31215680
http://dx.doi.org/10.1002/med.21601