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Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk

Cancer driver mutations (CDMs) are necessary and causal for carcinogenesis and have advantages as reporters of carcinogenic risk. However, little progress has been made toward developing measurements of CDMs as biomarkers for use in cancer risk assessment. Impediments for using a CDM‐based metric to...

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Detalles Bibliográficos
Autores principales: Harris, Kelly L., Myers, Meagan B., McKim, Karen L., Elespuru, Rosalie K., Parsons, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973253/
https://www.ncbi.nlm.nih.gov/pubmed/31469467
http://dx.doi.org/10.1002/em.22326