Sequencing‐based microsatellite instability testing using as few as six markers for high‐throughput clinical diagnostics

Microsatellite instability (MSI) testing of colorectal cancers (CRCs) is used to screen for Lynch syndrome (LS), a hereditary cancer‐predisposition, and can be used to predict response to immunotherapy. Here, we present a single‐molecule molecular inversion probe and sequencing‐based MSI assay and d...

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Detalles Bibliográficos
Autores principales: Gallon, Richard, Sheth, Harsh, Hayes, Christine, Redford, Lisa, Alhilal, Ghanim, O'Brien, Ottilia, Spiewak, Helena, Waltham, Amanda, McAnulty, Ciaron, Izuogu, Osagie G., Arends, Mark J., Oniscu, Anca, Alonso, Angel M., Laguna, Sira M., Borthwick, Gillian M., Santibanez‐Koref, Mauro, Jackson, Michael S., Burn, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973255/
https://www.ncbi.nlm.nih.gov/pubmed/31471937
http://dx.doi.org/10.1002/humu.23906

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