Improved Stability and Tunable Functionalization of Parallel β‐Sheets via Multicomponent N‐Alkylation of the Turn Moiety

In contrast to the myriad of methods available to produce α‐helices and antiparallel β‐sheets in synthetic peptides, just a few are known for the construction of stable, non‐cyclic parallel β‐sheets. Herein, we report an efficient on‐resin approach for the assembly of parallel β‐sheet peptides in wh...

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Detalles Bibliográficos
Autores principales: Ricardo, Manuel G., Moya, Celia G., Pérez, Carlos S., Porzel, Andrea, Wessjohann, Ludger A., Rivera, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973259/
https://www.ncbi.nlm.nih.gov/pubmed/31797518
http://dx.doi.org/10.1002/anie.201912095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973259/
https://www.ncbi.nlm.nih.gov/pubmed/31797518
http://dx.doi.org/10.1002/anie.201912095

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