Divergent effects of translation termination factor eRF3A and nonsense-mediated mRNA decay factor UPF1 on the expression of uORF carrying mRNAs and ribosome protein genes

In addition to its role in translation termination, eRF3A has been implicated in the nonsense-mediated mRNA decay (NMD) pathway through its interaction with UPF1. NMD is a RNA quality control mechanism, which detects and degrades aberrant mRNAs as well as some normal transcripts including those that...

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Detalles Bibliográficos
Autores principales: Aliouat, Affaf, Hatin, Isabelle, Bertin, Pierre, François, Pauline, Stierlé, Vérène, Namy, Olivier, Salhi, Samia, Jean-Jean, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973328/
https://www.ncbi.nlm.nih.gov/pubmed/31619139
http://dx.doi.org/10.1080/15476286.2019.1674595

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