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Gene expression noise in a complex artificial toxin expression system

Gene expression is an intrinsically stochastic process. Fluctuations in transcription and translation lead to cell-to-cell variations in mRNA and protein levels affecting cellular function and cell fate. Here, using fluorescence time-lapse microscopy, we quantify noise dynamics in an artificial oper...

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Detalles Bibliográficos
Autores principales: Goetz, Alexandra, Mader, Andreas, von Bronk, Benedikt, Weiss, Anna S., Opitz, Madeleine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974158/
https://www.ncbi.nlm.nih.gov/pubmed/31961890
http://dx.doi.org/10.1371/journal.pone.0227249