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T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity
Focal Adhesion Kinase (FAK) inhibitors are currently undergoing clinical testing in combination with anti-PD-1 immune checkpoint inhibitors. However, which patients are most likely to benefit from FAK inhibitors, and what the optimal FAK/immunotherapy combinations are, is currently unknown. We ident...
Autores principales: | Canel, Marta, Taggart, David, Sims, Andrew H, Lonergan, David W, Waizenegger, Irene C, Serrels, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974352/ https://www.ncbi.nlm.nih.gov/pubmed/31959281 http://dx.doi.org/10.7554/eLife.48092 |
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