Podoplanin Gene Disruption in Mice Promotes in vivo Neural Progenitor Cells Proliferation, Selectively Impairs Dentate Gyrus Synaptic Depression and Induces Anxiety-Like Behaviors

Podoplanin (Pdpn), a brain-tumor-related glycoprotein identified in humans and animals, is endogenously expressed in several organs critical for life support such as kidney, lung, heart and brain. In the brain, Pdpn has been identified in proliferative nestin-positive adult neural progenitor cells a...

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Detalles Bibliográficos
Autores principales: Cicvaric, Ana, Sachernegg, Hannah M., Stojanovic, Tamara, Symmank, Dörte, Smani, Tarik, Moeslinger, Thomas, Uhrin, Pavel, Monje, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974453/
https://www.ncbi.nlm.nih.gov/pubmed/32009902
http://dx.doi.org/10.3389/fncel.2019.00561

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