Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1

The major causes of emergence of multidrug-resistant organisms (MDRO) in neonatal sepsis include empiric antibiotic prescriptions, unregulated use of over-the-counter drugs, high incidence of healthcare associated infections (HAI), lack of awareness about antibiotic stewardship program and under sta...

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Detalles Bibliográficos
Autores principales: Wattal, Chand, Kler, Neelam, Oberoi, J. K., Fursule, Anurag, Kumar, Anup, Thakur, Anup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974503/
https://www.ncbi.nlm.nih.gov/pubmed/31828600
http://dx.doi.org/10.1007/s12098-019-03106-z
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author Wattal, Chand
Kler, Neelam
Oberoi, J. K.
Fursule, Anurag
Kumar, Anup
Thakur, Anup
author_facet Wattal, Chand
Kler, Neelam
Oberoi, J. K.
Fursule, Anurag
Kumar, Anup
Thakur, Anup
author_sort Wattal, Chand
collection PubMed
description The major causes of emergence of multidrug-resistant organisms (MDRO) in neonatal sepsis include empiric antibiotic prescriptions, unregulated use of over-the-counter drugs, high incidence of healthcare associated infections (HAI), lack of awareness about antibiotic stewardship program and under staffing of neonatal intensive care units. In general, mortality due to MDRO sepsis is significantly higher as compared to non MDRO sepsis. Reported morbidities include prolonged use of total parenteral nutrition, need for central venous catheter, invasive ventilation, increased duration of hospital stay and neurologic sequelae.
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spelling pubmed-69745032020-02-03 Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1 Wattal, Chand Kler, Neelam Oberoi, J. K. Fursule, Anurag Kumar, Anup Thakur, Anup Indian J Pediatr Review Article The major causes of emergence of multidrug-resistant organisms (MDRO) in neonatal sepsis include empiric antibiotic prescriptions, unregulated use of over-the-counter drugs, high incidence of healthcare associated infections (HAI), lack of awareness about antibiotic stewardship program and under staffing of neonatal intensive care units. In general, mortality due to MDRO sepsis is significantly higher as compared to non MDRO sepsis. Reported morbidities include prolonged use of total parenteral nutrition, need for central venous catheter, invasive ventilation, increased duration of hospital stay and neurologic sequelae. Springer India 2019-12-11 2020 /pmc/articles/PMC6974503/ /pubmed/31828600 http://dx.doi.org/10.1007/s12098-019-03106-z Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review Article
Wattal, Chand
Kler, Neelam
Oberoi, J. K.
Fursule, Anurag
Kumar, Anup
Thakur, Anup
Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1
title Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1
title_full Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1
title_fullStr Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1
title_full_unstemmed Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1
title_short Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1
title_sort neonatal sepsis: mortality and morbidity in neonatal sepsis due to multidrug-resistant (mdr) organisms: part 1
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974503/
https://www.ncbi.nlm.nih.gov/pubmed/31828600
http://dx.doi.org/10.1007/s12098-019-03106-z
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