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Endogenous T Cell Receptor Rearrangement Represses Aggressive Central Nervous System Autoimmunity in a TcR-Transgenic Model on the Non-Obese Diabetic Background

The T cell response to central nervous system (CNS) antigen in experimental autoimmune encephalomyelitis (EAE) permits one to model the immune aspects of multiple sclerosis. 1C6 transgenic mice on the non-obese diabetic (NOD) background possess a class II-restricted T cell receptor (TcR; Vα5-Vβ7) sp...

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Detalles Bibliográficos
Autores principales:	Yeola, Asmita Pradeep, Ignatius Arokia Doss, Prenitha Mercy, Baillargeon, Joanie, Akbar, Irshad, Mailhot, Benoit, Balood, Mohammad, Talbot, Sébastien, Anderson, Ana Carrizosa, Lacroix, Steve, Rangachari, Manu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974510/ https://www.ncbi.nlm.nih.gov/pubmed/32010149 http://dx.doi.org/10.3389/fimmu.2019.03115

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