Cargando…
Digging Deeper to Save the Old Anti-tuberculosis Target: D-Alanine–D-Alanine Ligase With a Novel Inhibitor, IMB-0283
The emergence of drug-resistant Mycobacterium tuberculosis (Mtb) has hampered treatments for tuberculosis, which consequently now require novel agents to overcome such drug resistance. The genetically stable D-alanine–D-alanine ligase A (DdlA) has been deemed as an excellent therapeutic target for t...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974524/ https://www.ncbi.nlm.nih.gov/pubmed/32010089 http://dx.doi.org/10.3389/fmicb.2019.03017 |