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miR-20b-5p, TGFBR2, and E2F1 Form a Regulatory Loop to Participate in Epithelial to Mesenchymal Transition in Prostate Cancer

The transcription factor E2F1 regulates the expression of the miR-20b-5p precursor and is involved in epithelial-to-mesenchymal transition (EMT). Transforming growth factor-β1 (TGF-β1) induces EMT in prostate cancer (PCa) by binding to TGF-beta receptor 2 (TGFBR2) to activate TGF-β signaling. Howeve...

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Detalles Bibliográficos
Autores principales:	Qi, Jin-Chun, Yang, Zhan, Zhang, Yan-Ping, Lu, Bao-Sai, Yin, Yue-Wei, Liu, Kai-Long, Xue, Wen-Yong, Qu, Chang-Bao, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974577/ https://www.ncbi.nlm.nih.gov/pubmed/32010624 http://dx.doi.org/10.3389/fonc.2019.01535

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