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A tissue‐specific screen of ceramide expression in aged mice identifies ceramide synthase‐1 and ceramide synthase‐5 as potential regulators of fiber size and strength in skeletal muscle
Loss of skeletal muscle mass is one of the most widespread and deleterious processes in aging humans. However, the mechanistic metabolic principles remain poorly understood. In the framework of a multi‐organ investigation of age‐associated changes of ceramide species, a unique and distinctive change...
Autores principales: | Tosetti, Bettina, Brodesser, Susanne, Brunn, Anna, Deckert, Martina, Blüher, Matthias, Doehner, Wolfram, Anker, Stefan D., Wenzel, Daniela, Fleischmann, Bernd, Pongratz, Carola, Peters, Franziska, Utermöhlen, Olaf, Krönke, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974707/ https://www.ncbi.nlm.nih.gov/pubmed/31692231 http://dx.doi.org/10.1111/acel.13049 |
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