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Acetylation changes tau interactome to degrade tau in Alzheimer’s disease animal and organoid models
Alzheimer's disease (AD) is an age‐related neurodegenerative disease. The most common pathological hallmarks are amyloid plaques and neurofibrillary tangles in the brain. In the brains of patients with AD, pathological tau is abnormally accumulated causing neuronal loss, synaptic dysfunction, a...
Autores principales: | Choi, Heesun, Kim, Haeng Jun, Yang, Jinhee, Chae, Sehyun, Lee, Wonik, Chung, Sunwoo, Kim, Jisoo, Choi, Hyunjung, Song, Hyeseung, Lee, Chang Kon, Jun, Jae Hyun, Lee, Yong Jae, Lee, Kyunghyeon, Kim, Semi, Sim, Hye‐ri, Choi, Young Il, Ryu, Keun Ho, Park, Jong‐Chan, Lee, Dongjoon, Han, Sun‐Ho, Hwang, Daehee, Kyung, Jangbeen, Mook‐Jung, Inhee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974726/ https://www.ncbi.nlm.nih.gov/pubmed/31763743 http://dx.doi.org/10.1111/acel.13081 |
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