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Acetylation changes tau interactome to degrade tau in Alzheimer’s disease animal and organoid models

Alzheimer's disease (AD) is an age‐related neurodegenerative disease. The most common pathological hallmarks are amyloid plaques and neurofibrillary tangles in the brain. In the brains of patients with AD, pathological tau is abnormally accumulated causing neuronal loss, synaptic dysfunction, a...

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Detalles Bibliográficos
Autores principales: Choi, Heesun, Kim, Haeng Jun, Yang, Jinhee, Chae, Sehyun, Lee, Wonik, Chung, Sunwoo, Kim, Jisoo, Choi, Hyunjung, Song, Hyeseung, Lee, Chang Kon, Jun, Jae Hyun, Lee, Yong Jae, Lee, Kyunghyeon, Kim, Semi, Sim, Hye‐ri, Choi, Young Il, Ryu, Keun Ho, Park, Jong‐Chan, Lee, Dongjoon, Han, Sun‐Ho, Hwang, Daehee, Kyung, Jangbeen, Mook‐Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974726/
https://www.ncbi.nlm.nih.gov/pubmed/31763743
http://dx.doi.org/10.1111/acel.13081

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