4-AP-3-MeOH Promotes Structural and Functional Spontaneous Recovery in the Acute Sciatic Nerve Stretch Injury

BACKGROUND: 4-AP-3-MeOH, a derivative of 4-aminopyridine, was developed and demonstrated to prevent nerve pulse diffusion due to myelin damage and significantly enhance axonal conduction following nerve injury. Currently, repurposing the existing drug such as 4-AP-3-MeOH to restore motor function is...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yan, Wang, Weidong, Zhao, Zhimin, Ren, Dong, Xin, Danmou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Nanotechnology and Microtechnology in Drug Delivery Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974761/
https://www.ncbi.nlm.nih.gov/pubmed/32009855
http://dx.doi.org/10.1177/1559325819899254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974761/
https://www.ncbi.nlm.nih.gov/pubmed/32009855
http://dx.doi.org/10.1177/1559325819899254

Ejemplares similares