Involvement of Glutathione Depletion in Selective Cytotoxicity of Oridonin to p53-Mutant Esophageal Squamous Carcinoma Cells

Oridonin, a diterpenoid compound isolated from traditional Chinese medicine Rabdosia rubescens, has shown antitumor effects to esophageal cancer. However, its molecular mechanism is not fully understood, which limits its clinical application. In the present study, we used RNA-seq analysis to check t...

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Detalles Bibliográficos
Autores principales: Li, Yinchao, Li, Nana, Shi, Jianxiang, Ahmed, Tanzeel, Liu, Hongmin, Guo, Jiancheng, Tang, Wenxue, Guo, Yongjun, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974803/
https://www.ncbi.nlm.nih.gov/pubmed/32010620
http://dx.doi.org/10.3389/fonc.2019.01525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974803/
https://www.ncbi.nlm.nih.gov/pubmed/32010620
http://dx.doi.org/10.3389/fonc.2019.01525

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